Each year we make films for Genetic Disorders UK, the charity that runs the high profile Jeans for Genes Day, and aims to change the world for children with genetic disorders.

The films we make for them are watched the whole year round by teachers and pupils, as education resources for schools. In one of these films we followed Alfie, aged 14. Faced with an option to cure him of his life-limiting and life-threatening condition for good, he shared the personal journey of his bone marrow transplantation.

Alfie was born with chronic granulomatous disorder (CGD), a rare genetic blood condition that stops his immune system working properly, causing him repeated bouts of serious infection often resulting in pneumonia and abscesses of the skin, tissues and organs. Our team filmed with him at home and throughout the bone marrow transplantation process at University College Hospital, London, over a six month period.